Genetics and Reproduction: IVF and ICSI with PGD

Based on Reproductive genetics understanding, therapies are developed and used to maximize outcomes.

Specifically, increased pregnancy rates,decreased incidence of obstetric complications and miscarriage, and the avoidance of fetuses affected by birth defects or other deficiencies are the stated goal of much of the current research in reproductive medicine. The role of genetic testing to guide medical decision making in this regard is sizable and will likely continue to grow in the future.

Genetic evaluations within reproductive medicine may be subdivided into 4 main categories:

1. Preconception genetic testing: The genetic evaluation of prospective parents before pregnancy.

2. Antenatal genetic testing: The genetic evaluation of women who are currently pregnant to determine  the genetic makeup of the developing fetus.

3. Preimplantation genetic testing ( PGD and PGS): The genetic evaluation of an embryo, before uterine transfer, via an embryo biopsy during an in-vitro fertilization (IVF) procedure.

4. Genetic analysis following fetal demise: The genetic evaluation  of the product of conception following a failed pregnancy.

 

Cost cutting in IVF ICSI treatment.

Cost cutting can be done by multiple ways in IVF treatment.

One of the most important aspect is Drugs used in IVF treatment.

Low cost IVF can be done if we use Urinary derived gonadotropins.

Now a days, may be because of market pressure or because of misinformation, many IVF centers started using Recombinant Gonadotropins in place of age old urinary gonadotropins.

Do you know that Urinary products, esp Human Menopausal Gonadotropin(HMG) gives better results that Recombinant(Rec FSH) ones ( Ref: Cinics Review Articles in ObGy clinic of north america March 2015).

HMG is one third of the cost of Rec FSH. Hence we made our cost structure IVF may be one fifth to one sixth of many IVF Centers in world.

We use mostly HMG  and it gives very good Blastocysts. Very good IVF success rates, some times the implantation rate goes up to 80-85%. But over all implantation rate is 60-65%